Upton attended the casting call in Miami for Elite Model Management in 2008 , and was signed by them on the same day. Finally I moved to New York City, where it took place after the models with IMG
Upton as the first garage, and Dooney & Burke. 2010-11 It is the face of speculation. In 2011, Upton appeared in Sports Illustrated swimsuit issue. Was featured in the text of Section paint and named Rookie of the Year of the issue. as she has for the Beach Bunny Swimwear and Victoria’s Secret, and appeared in the complex . Esquire as “Women in the summer.
In April 2011 video on the Internet to do the “Dougie” in a game Los Angeles Clippers went viral and that contributed to the increase in popularity.   On April 30, 2012, the Upton bikini clad performance of “cat daddy” in a video directed by Terry Richardson also went viral, and to mobilize nearly 750,000 views in 24 hours before it was temporarily removed from the YouTube for violating the rules of content on the site.
Upton made an appearance in an episode of the 2011 June Tosh.0, and participate in a piece called “a knife or a banana,” a simulation of the Japanese game show that is stabbed her with a banana.
Upton played in 2011 Taco Bell Legends and Celebrity All-Star baseball game at Chase Field in Phoenix, Arizona, in July 2011.
Her first appearance in Upton representation in the Tower Heist movie, as Mr. Hightower’s Mistress. She followed with an appearance in the three stooges as Sister Bernice.
Upton appeared on the cover of issue 2012 Swimsuit Sports Illustrated, revealed in the February 13, 2012, on display in late with David Letterman.Upton appeared on Saturday Night Live on February 18, 2012 in a graphic with the East as a guest. and again in 2012, appeared on more covers, in magazines such as Esquire, Moses, and TV commercial for Carl Jr., and US-based fast food chain.Upton appeared in Major League Baseball 2K12 trade with the Detroit Tigers pitcher Justin Verlander, Tampa Bay pitcher David Price Rise, Los Angeles Angels of Anaheim pitcher CJ Wilson, and Cincinnati Reds Jay Bruce defending player.